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内容説明
Professor Michael N. Marsh， a recognized world authority on this condition， together with a team of other expert laboratory/clinical investigators from around the world， present a collection of the state-of-the-art techniques for studying the biology and immunopathology of celiac disease. Both the novice and experienced researcher will find in this collection detailed step-by-step methods for cloning lymphocytes， creating gene/peptide libraries， and performing genotyping， linkage， and positional cloning. Also included are techniques for determining the peptide structure of HLA-bound material (tandem mass spectroscopy)， computerized morphometry， in situ hybridization， organ culture， and monoclonal AB assays. Comprehensive and cutting-edge， Celiac Disease: Methods and Protocols provides all experimental and clinical investigators with the essential core of readily reproducible methods necessary for successful work on celiac disease today.
Book Description
Univ. of Manchester， Salford， UK. Collection of techniques for studying the biology and immunopathology of celiac disease. Detailed methods for cloning lymphocytes， creating gene/peptide libraries， and performing genotyping， linkage， and positional cloning. For researchers. DNLM: Celiac Disease--immunology.